Showing CypComp Card for CC02383: Disopyramide (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:53:33 UTC
Last Updated2019-10-01 21:42:01 UTC
CypComp IDCC02383
Compound Information
NameDisopyramide
Structure ImageUvtnfzqiczkoem nrfanrhfsa n
InChIKeyUVTNFZQICZKOEM-NRFANRHFSA-N
PubChem ID156295
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <2,4;Cleavage;R1>
  • <2,H;Oxidation;R1>
  • <23,4;Cleavage;R2>
  • <23,H;Oxidation;R2>
References
  1. Echizen H, Tanizaki M, Tatsuno J, Chiba K, Berwick T, Tani M, Gonzalez FJ, Ishizaki T: Identification of CYP3A4 as the enzyme involved in the mono-N-dealkylation of disopyramide enantiomers in humans. Drug Metab Dispos. 2000 Aug;28(8):937-44. [PubMed:10901704 ]
Download FileCC02383.sdf