Record Information
Version1.0
Creation Date2019-07-14 16:54:52 UTC
Last Updated2019-10-01 21:42:02 UTC
CypComp IDCC02388
Compound Information
NameEplerenone
Structure ImageJukpwjgbannwmw vwbfhtrksa n
InChIKeyJUKPWJGBANNWMW-VWBFHTRKSA-N
PubChem ID443872
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <14,H;Hydroxylation;R1>
  • <28,H;Hydroxylation;R2>
References
  1. Cook CS, Berry LM, Kim DH, Burton EG, Hribar JD, Zhang L: Involvement of CYP3A in the metabolism of eplerenone in humans and dogs: differential metabolism by CYP3A4 and CYP3A5. Drug Metab Dispos. 2002 Dec;30(12):1344-51. doi: 10.1124/dmd.30.12.1344. [PubMed:12433801 ]
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