Showing CypComp Card for CC02396: Finasteride (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:54:54 UTC
Last Updated2019-10-01 21:42:03 UTC
CypComp IDCC02396
Compound Information
NameFinasteride
Structure ImageDbeplocgeieocv wsbqpabssa n
InChIKeyDBEPLOCGEIEOCV-WSBQPABSSA-N
PubChem ID57363
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <25,H;Hydroxylation;R1>
  • <26,H;Hydroxylation;R2>
  • <27,H;Hydroxyaltion;R3>
References
  1. Guengerich FP: Cytochrome P-450 3A4: regulation and role in drug metabolism. Annu Rev Pharmacol Toxicol. 1999;39:1-17. doi: 10.1146/annurev.pharmtox.39.1.1. [PubMed:10331074 ]
  2. Huskey SW, Dean DC, Miller RR, Rasmusson GH, Chiu SH: Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride. Drug Metab Dispos. 1995 Oct;23(10):1126-35. [PubMed:8654202 ]
Download FileCC02396.sdf