Showing CypComp Card for CC02403: Indinavir (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:54:56 UTC
Last Updated2019-10-01 21:42:04 UTC
CypComp IDCC02403
Compound Information
NameIndinavir
Structure ImageCbvczfgxhxorbi pxqqmzjssa n
InChIKeyCBVCZFGXHXORBI-PXQQMZJSSA-N
PubChem ID5362440
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <44,N;N-Oxidation;R1>
  • <35,32;Cleavage;R2>
  • <35,H;Oxidation;R2>
  • <26,H;Hydroxylation;R3>
  • <7,H;Hydroxylation;R4>
References
  1. Chiba M, Hensleigh M, Lin JH: Hepatic and intestinal metabolism of indinavir, an HIV protease inhibitor, in rat and human microsomes. Major role of CYP3A. Biochem Pharmacol. 1997 Apr 25;53(8):1187-95. doi: 10.1016/s0006-2952(97)00100-7. [PubMed:9175724 ]
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