Showing CypComp Card for CC02404: Irinotecan (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:54:56 UTC
Last Updated2019-10-01 21:42:04 UTC
CypComp IDCC02404
Compound Information
NameIrinotecan
Structure ImageUwkqsnnfcggafs xiffeerxsa n
InChIKeyUWKQSNNFCGGAFS-XIFFEERXSA-N
PubChem ID60838
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <37,20;Cleavage;R1>
  • <37,H;Oxidation;R1>
  • <38,20;Cleavage;R2>
  • <38,H;Oxidation;R2>
References
  1. Sai K, Kaniwa N, Ozawa S, Sawada JI: A new metabolite of irinotecan in which formation is mediated by human hepatic cytochrome P-450 3A4. Drug Metab Dispos. 2001 Nov;29(11):1505-13. [PubMed:11602529 ]
Download FileCC02404.sdf