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Showing CypComp Card for CC02407: Ivermectin (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:54:57 UTC
Last Updated2019-10-01 21:42:05 UTC
CypComp IDCC02407
Compound Information
NameIvermectin
Structure ImageQsenxekzwyffjk fklturbqsa n
InChIKeyQSENXEKZWYFFJK-FKLTURBQSA-N
PubChem IDNot Available
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <59,56;Cleavage;R1>
  • <59,H;Oxidation;R1>
  • <42,H;Hydroxylation;R2>
  • <17,H;Hydroxylation;R3>
References
  1. Zeng Z, Andrew NW, Arison BH, Luffer-Atlas D, Wang RW: Identification of cytochrome P4503A4 as the major enzyme responsible for the metabolism of ivermectin by human liver microsomes. Xenobiotica. 1998 Mar;28(3):313-21. doi: 10.1080/004982598239597. [PubMed:9574819 ]
Download FileCC02407.sdf