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Record Information
Version1.0
Creation Date2019-07-14 16:54:57 UTC
Last Updated2019-10-01 21:42:05 UTC
CypComp IDCC02410
Compound Information
NameLaquinimod
Structure ImageGkwpceffihsjoe uhfffaoysa n
InChIKeyGKWPCEFFIHSJOE-UHFFFAOYSA-N
PubChem ID54677946
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <13,H;Hydroxylation;R1>
  • <9,H;Hydroxylation;R2>
  • <6,H;Hydroxylation;R3>
  • <12,5;Cleavage;R4>
  • <12,H;Oxidation;R4>
  • <25,H;Hydroxylation;R5>
  • <19,16;Cleavage;R6>
  • <19,H;Oxidation;R6>
References
  1. Tuvesson H, Hallin I, Persson R, Sparre B, Gunnarsson PO, Seidegard J: Cytochrome P450 3A4 is the major enzyme responsible for the metabolism of laquinimod, a novel immunomodulator. Drug Metab Dispos. 2005 Jun;33(6):866-72. doi: 10.1124/dmd.104.002238. Epub 2005 Mar 11. [PubMed:15764719 ]
Download FileCC02410.sdf