Showing CypComp Card for CC02413: Lovastatin (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:54:58 UTC
Last Updated2019-10-01 21:42:06 UTC
CypComp IDCC02413
Compound Information
NameLovastatin
Structure ImagePczohlxuxfiocf bxmdzjjmsa n
InChIKeyPCZOHLXUXFIOCF-BXMDZJJMSA-N
PubChem ID53232
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <27,H;Hydroxylation;R1>
  • <2,H;Hydroxylation;R2>
References
  1. Jacobsen W, Kirchner G, Hallensleben K, Mancinelli L, Deters M, Hackbarth I, Benet LZ, Sewing KF, Christians U: Comparison of cytochrome P-450-dependent metabolism and drug interactions of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors lovastatin and pravastatin in the liver. Drug Metab Dispos. 1999 Feb;27(2):173-9. [PubMed:9929499 ]
Download FileCC02413.sdf