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Showing CypComp Card for CC02417: Mifepristone (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:54:59 UTC
Last Updated2019-10-01 21:42:06 UTC
CypComp IDCC02417
Compound Information
NameMifepristone
Structure ImageVkhahzoousrjna gcnjzuomsa n
InChIKeyVKHAHZOOUSRJNA-GCNJZUOMSA-N
PubChem ID55245
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <1,2;Cleavage;R1>
  • <1,H;Oxidation;R1>
  • <3,2;Cleavage;R2>
  • <3,H;Oxidation;R2>
  • <32,H;Hydroxylation;R3>
References
  1. Jang GR, Wrighton SA, Benet LZ: Identification of CYP3A4 as the principal enzyme catalyzing mifepristone (RU 486) oxidation in human liver microsomes. Biochem Pharmacol. 1996 Sep 13;52(5):753-61. doi: 10.1016/0006-2952(96)00357-7. [PubMed:8765473 ]
Download FileCC02417.sdf