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Record Information
Version1.0
Creation Date2019-07-14 16:55:02 UTC
Last Updated2019-10-01 21:42:07 UTC
CypComp IDCC02423
Compound Information
NameNifedipine
Structure ImageHyimsnhjobljnt uhfffaoysa n
InChIKeyHYIMSNHJOBLJNT-UHFFFAOYSA-N
PubChem ID4485
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <10,H;Oxidation;R1>
  • <10,11;Oxidation;R1>
  • <11,12;Reduction;R1>
  • <12,7;Oxidation;R1>
  • <7,8;Oxidation;R1>
  • <8,9;Reduction;R1>
  • <9,10;Oxidation;R1>
  • <7,H;Oxidation;R1>
References
  1. Guengerich FP, Martin MV, Beaune PH, Kremers P, Wolff T, Waxman DJ: Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism. J Biol Chem. 1986 Apr 15;261(11):5051-60. [PubMed:3514607 ]
Download FileCC02423.sdf