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Showing CypComp Card for CC02424: Nitrendipine (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:55:02 UTC
Last Updated2019-10-01 21:42:07 UTC
CypComp IDCC02424
Compound Information
NameNitrendipine
Structure ImagePvhujelljljgln mrxnpfedsa n
InChIKeyPVHUJELLJLJGLN-MRXNPFEDSA-N
PubChem ID157704
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <10,H;Oxidation;R1>
  • <10,11;Oxidation;R1>
  • <11,12;Reduction;R1>
  • <12,7;Oxidation;R1>
  • <7,8;Oxidation;R1>
  • <8,9;Reduction;R1>
  • <9,10;Oxidation;R1>
  • <7,H;Oxidation;R1>
References
  1. Guengerich FP, Brian WR, Iwasaki M, Sari MA, Baarnhielm C, Berntsson P: Oxidation of dihydropyridine calcium channel blockers and analogues by human liver cytochrome P-450 IIIA4. J Med Chem. 1991 Jun;34(6):1838-44. doi: 10.1021/jm00110a012. [PubMed:2061924 ]
Download FileCC02424.sdf