Showing CypComp Card for CC02440: Rifabutin (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:55:07 UTC
Last Updated2019-10-01 21:42:09 UTC
CypComp IDCC02440
Compound Information
NameRifabutin
Structure ImageCnazmmbryqfsbi aexanhcbsa n
InChIKeyCNAZMMBRYQFSBI-AEXANHCBSA-N
PubChem IDNot Available
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <52,H;Hydroxylation;R1>
  • <61,H;Hydroxylation;R2>
  • <48,H;Hydroxylation;R3>
  • <47,41;Cleavage;R4>
  • <47,H;Oxidation;R4>
References
  1. Iatsimirskaia E, Tulebaev S, Storozhuk E, Utkin I, Smith D, Gerber N, Koudriakova T: Metabolism of rifabutin in human enterocyte and liver microsomes: kinetic parameters, identification of enzyme systems, and drug interactions with macrolides and antifungal agents. Clin Pharmacol Ther. 1997 May;61(5):554-62. doi: 10.1016/S0009-9236(97)90135-1. [PubMed:9164417 ]
Download FileCC02440.sdf