Record Information |
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Version | 1.0 |
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Creation Date | 2019-07-14 16:55:08 UTC |
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Last Updated | 2019-10-01 21:42:09 UTC |
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CypComp ID | CC02444 |
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Compound Information |
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Name | Roxithromycin |
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Structure Image | |
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InChIKey | RXZBMPWDPOLZGW-FZWLNVMRSA-N |
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PubChem ID | Not Available |
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CypCompound Information |
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Set | CypBoM Training Set |
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Bonds of Metabolism (BoMs) | CYP1A2 | CYP2A6 | CYP2B6 | CYP2C8 | CYP2C9 | CYP2C19 | CYP2D6 | CYP2E1 | CYP3A4 | | | | | | | | | - <49,44;Cleavage;R1>
- <49,H;Oxidation;R1>
- <50,44;Cleavage;R2>
- <50,H;Oxidation;R2>
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References | - Yamazaki H, Shimada T: Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin. Drug Metab Dispos. 1998 Nov;26(11):1053-7. [PubMed:9806945 ]
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Download File | CC02444.sdf |
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