Showing CypComp Card for CC02444: Roxithromycin (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:55:08 UTC
Last Updated2019-10-01 21:42:09 UTC
CypComp IDCC02444
Compound Information
NameRoxithromycin
Structure ImageRxzbmpwdpolzgw fzwlnvmrsa n
InChIKeyRXZBMPWDPOLZGW-FZWLNVMRSA-N
PubChem IDNot Available
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <49,44;Cleavage;R1>
  • <49,H;Oxidation;R1>
  • <50,44;Cleavage;R2>
  • <50,H;Oxidation;R2>
References
  1. Yamazaki H, Shimada T: Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin. Drug Metab Dispos. 1998 Nov;26(11):1053-7. [PubMed:9806945 ]
Download FileCC02444.sdf