Showing CypComp Card for CC02447: Saquinavir (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:55:09 UTC
Last Updated2019-10-01 21:42:09 UTC
CypComp IDCC02447
Compound Information
NameSaquinavir
Structure ImageQwaxkhkrtorlem ugjkxsetsa n
InChIKeyQWAXKHKRTORLEM-UGJKXSETSA-N
PubChem ID441243
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <12,H;Hydroxylation;R1>
References
  1. Fitzsimmons ME, Collins JM: Selective biotransformation of the human immunodeficiency virus protease inhibitor saquinavir by human small-intestinal cytochrome P4503A4: potential contribution to high first-pass metabolism. Drug Metab Dispos. 1997 Feb;25(2):256-66. [PubMed:9029057 ]
Download FileCC02447.sdf