Showing CypComp Card for CC02458: Trazodone (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:55:12 UTC
Last Updated2019-10-01 21:42:12 UTC
CypComp IDCC02458
Compound Information
NameTrazodone
Structure ImagePhlbkphsavxxef uhfffaoysa n
InChIKeyPHLBKPHSAVXXEF-UHFFFAOYSA-N
PubChem ID5533
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <13,14;Cleavage;R1>
  • <13,H;Oxidation;R1>
  • <23,H;Hydroxylation;R2>
  • <1,3;Epoxidation;R3>
References
  1. Wen B, Ma L, Rodrigues AD, Zhu M: Detection of novel reactive metabolites of trazodone: evidence for CYP2D6-mediated bioactivation of m-chlorophenylpiperazine. Drug Metab Dispos. 2008 May;36(5):841-50. doi: 10.1124/dmd.107.019471. Epub 2008 Jan 31. [PubMed:18238857 ]
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