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Record Information
Version1.0
Creation Date2019-07-14 16:55:15 UTC
Last Updated2019-10-01 21:42:13 UTC
CypComp IDCC02471
Compound Information
NameAprepitant M1
Structure ImageAfbdsajomzyqai cnozutplsa n
InChIKeyAFBDSAJOMZYQAI-CNOZUTPLSA-N
PubChem ID10113945
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <1,5;DeHydrogenation;R1>
References
  1. Sanchez RI, Wang RW, Newton DJ, Bakhtiar R, Lu P, Chiu SH, Evans DC, Huskey SE: Cytochrome P450 3A4 is the major enzyme involved in the metabolism of the substance P receptor antagonist aprepitant. Drug Metab Dispos. 2004 Nov;32(11):1287-92. doi: 10.1124/dmd.104.000216. Epub 2004 Aug 10. [PubMed:15304427 ]
Download FileCC02471.sdf