Record Information
Version1.0
Creation Date2019-07-14 16:55:16 UTC
Last Updated2019-10-01 21:42:13 UTC
CypComp IDCC02475
Compound Information
NameFK-506-M1
Structure ImageOkrzoxiqnkytbl znpyslgisa n
InChIKeyOKRZOXIQNKYTBL-ZNPYSLGISA-N
PubChem IDNot Available
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <14,9;Cleavage;R1>
  • <14,H;Oxidation;R1>
References
  1. Vincent SH, Karanam BV, Painter SK, Chiu SH: In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism. Arch Biochem Biophys. 1992 May 1;294(2):454-60. doi: 10.1016/0003-9861(92)90711-5. [PubMed:1373595 ]
Download FileCC02475.sdf