Record Information |
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Version | 1.0 |
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Creation Date | 2019-07-14 16:55:17 UTC |
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Last Updated | 2019-10-01 21:42:14 UTC |
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CypComp ID | CC02479 |
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Compound Information |
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Name | TPA023 |
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Structure Image | |
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InChIKey | QKIWQBLNTSQOLY-UHFFFAOYSA-N |
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PubChem ID | 9908684 |
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CypCompound Information |
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Set | CypBoM Training Set |
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Bonds of Metabolism (BoMs) | CYP1A2 | CYP2A6 | CYP2B6 | CYP2C8 | CYP2C9 | CYP2C19 | CYP2D6 | CYP2E1 | CYP3A4 | | | | | | | | | - <28,27;Cleavage;R1>
- <21,H;Hydroxylation;R2>
- <20,H;Hydroxylation;R3>
- <19,H;Hydroxylation;R4>
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References | - Ma B, Polsky-Fisher SL, Vickers S, Cui D, Rodrigues AD: Cytochrome P450 3A-dependent metabolism of a potent and selective gamma-aminobutyric acid Aalpha2/3 receptor agonist in vitro: involvement of cytochrome P450 3A5 displaying biphasic kinetics. Drug Metab Dispos. 2007 Aug;35(8):1301-7. doi: 10.1124/dmd.107.014753. Epub 2007 Apr 25. [PubMed:17460031 ]
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Download File | CC02479.sdf |
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