Record Information
Version1.0
Creation Date2019-07-14 16:55:29 UTC
Last Updated2019-10-01 21:42:17 UTC
CypComp IDCC02502
Compound Information
NameCarbosulfan
Structure ImageJlqufihwvlzvtj uhfffaoysa n
InChIKeyJLQUFIHWVLZVTJ-UHFFFAOYSA-N
PubChem ID41384
CypCompound Information
SetCypBoM Testing Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <14,15;Cleavage;R1>
  • <14,15;Cleavage;R1>
  • <14,15;Cleavage;R1>
  • <15,S;S-Oxidation;R2>
  • <14,15;Cleavage;R1>
  • Not Available
  • <14,15;Cleavage;R1>
  • <15,S;S-Oxidation;R2>
  • Not Available
  • Not Available
  • <14,15;Cleavage;R1>
  • <15,S;S-Oxidation;R2>
References
  1. Abass K, Reponen P, Mattila S, Pelkonen O: Metabolism of carbosulfan II. Human interindividual variability in its in vitro hepatic biotransformation and the identification of the cytochrome P450 isoforms involved. Chem Biol Interact. 2010 May 14;185(3):163-73. doi: 10.1016/j.cbi.2010.03.024. Epub 2010 Mar 20. [PubMed:20307514 ]
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