Record Information |
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Version | 1.0 |
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Creation Date | 2019-07-14 16:55:34 UTC |
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Last Updated | 2019-10-01 21:42:20 UTC |
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CypComp ID | CC02520 |
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Compound Information |
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Name | N-Desmethyltamoxifen |
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Structure Image | |
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InChIKey | NYDCDZSEEAUOHN-IZHYLOQSSA-N |
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PubChem ID | 6378383 |
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CypCompound Information |
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Set | CypBoM Testing Set |
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Bonds of Metabolism (BoMs) | CYP1A2 | CYP2A6 | CYP2B6 | CYP2C8 | CYP2C9 | CYP2C19 | CYP2D6 | CYP2E1 | CYP3A4 | | | | | | | | | - <25,24;Cleavage;R1>
- <25,H;Oxidation;R1>
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References | - Brown CM, Reisfeld B, Mayeno AN: Cytochromes P450: a structure-based summary of biotransformations using representative substrates. Drug Metab Rev. 2008;40(1):1-100. doi: 10.1080/03602530802309742. [PubMed:18259985 ]
- Wang B, Zhou SF: Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr Med Chem. 2009;16(31):4066-218. [PubMed:19754423 ]
- Zhou SF: Polymorphism of human cytochrome P450 2D6 and its clinical significance: part II. Clin Pharmacokinet. 2009;48(12):761-804. doi: 10.2165/11318070-000000000-00000. [PubMed:19902987 ]
- Rendic S: Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metab Rev. 2002 Feb-May;34(1-2):83-448. doi: 10.1081/DMR-120001392. [PubMed:11996015 ]
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Download File | CC02520.sdf |
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