Showing CypComp Card for CC02539: Sevoflurane (CypBoM Testing Set)

Record Information
Version1.0
Creation Date2019-07-14 16:55:43 UTC
Last Updated2019-10-01 21:42:22 UTC
CypComp IDCC02539
Compound Information
NameSevoflurane
Structure ImageDfeyyrmxojxzrj uhfffaoysa n
InChIKeyDFEYYRMXOJXZRJ-UHFFFAOYSA-N
PubChem ID5206
CypCompound Information
SetCypBoM Testing Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • <12,8;Cleavage;R1>
  • <12,H;Oxidation;R1>
  • <12,8;Cleavage;R1>
  • <12,H;Oxidation;R1>
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <12,8;Cleavage;R1>
  • <12,H;Oxidation;R1>
  • <12,8;Cleavage;R1>
  • <12,H;Oxidation;R1>
References
  1. Kharasch ED, Hankins DC, Thummel KE: Human kidney methoxyflurane and sevoflurane metabolism. Intrarenal fluoride production as a possible mechanism of methoxyflurane nephrotoxicity. Anesthesiology. 1995 Mar;82(3):689-99. doi: 10.1097/00000542-199503000-00011. [PubMed:7879937 ]
  2. Chang GW, Kam PC: The physiological and pharmacological roles of cytochrome P450 isoenzymes. Anaesthesia. 1999 Jan;54(1):42-50. doi: 10.1046/j.1365-2044.1999.00602.x. [PubMed:10209369 ]
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