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Record Information
Version1.0
Creation Date2019-07-14 16:55:46 UTC
Last Updated2019-10-01 21:42:23 UTC
CypComp IDCC02545
Compound Information
NameFlunarizine
Structure ImageSmanxxcatutddt qpjjxvbhsa n
InChIKeySMANXXCATUTDDT-QPJJXVBHSA-N
PubChem ID941361
CypCompound Information
SetCypBoM Testing Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <7,3;Cleavage;R1>
  • <7,H;Oxidation;R1>
  • <10,4;Cleavage;R2>
  • <10,H;Oxidation;R2>
  • <7,3;Cleavage;R1>
  • <7,H;Oxidation;R1>
  • <10,4;Cleavage;R2>
  • <10,H;Oxidation;R2>
  • Not Available
  • Not Available
  • <7,3;Cleavage;R1>
  • <7,H;Oxidation;R1>
  • <10,4;Cleavage;R2>
  • <10,H;Oxidation;R2>
  • Not Available
  • <30,H;Hydroxylation;R1>
  • Not Available
  • Not Available
References
  1. Rendic S: Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metab Rev. 2002 Feb-May;34(1-2):83-448. doi: 10.1081/DMR-120001392. [PubMed:11996015 ]
  2. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
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